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NSUN2 Mouse anti-Human, Clone: 2H5A2, Proteintech
SDP

Catalog No. 501736998 Shop All Proteintech Group Inc Products
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50-173-6998 150 μL
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Catalog No. 50-173-6998 Supplier Proteintech Group Inc Supplier No. 665801IG150UL
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Mouse Monoclonal Antibody

NSUN2 encodes a methyltransferase that catalyzes the intron-dependent formation of 5-methylcytosine at C34 of tRNA-leu(CAA). Maturation of cytoplasmic tRNAs includes splicing of introns, which are located 1 nucleotide 3-prime from the anticodon in all intron-containing tRNA genes. In tRNA-leu(CAA), the first position of the anticodon, C34, is converted to 5-methylcytosine, a modification necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Mutations of NSUN2 result in autosomal recessive 5 mental retardation (MRT5).

Specifications

Antigen NSUN2
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 2H5A2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene NSUN2
Gene Accession No. Q08J23
Gene Alias hTrm4, MISU, NSUN2, SAKI, TRM4
Gene Symbols NSUN2
Host Species Mouse
Immunogen NSUN2 Fusion Protein Ag14791
Purification Method Protein A
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54888
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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