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Invitrogen™ NSUN2 Recombinant Rabbit Monoclonal Antibody (PSH05-05)
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Catalog No. MA556501
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MA556501 100 μL
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Catalog No. MA556501 Supplier Invitrogen™ Supplier No. MA556501
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Rabbit Recombinant Monoclonal Antibody

NSUN2 Recombinant Monoclonal Antibody for ICC/IF, IHC (P), IP, Western Blot

NSUN2 encodes a methyltransferase that catalyzes the intron-dependent formation of 5-methylcytosine at C34 of tRNA-leu(CAA). Maturation of cytoplasmic tRNAs includes splicing of introns, which are located 1 nucleotide 3-prime from the anticodon in all intron-containing tRNA genes. In tRNA-leu(CAA), the first position of the anticodon, C34, is converted to 5-methylcytosine, a modification necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Mutations of NSUN2 result in autosomal recessive 5 mental retardation (MRT5).
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Specifications

Antigen NSUN2
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone PSH05-05
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene NSUN2
Gene Accession No. Q08J23, Q1HFZ0
Gene Alias 5-methycytoisine methyltransferase; D13Wsu123e; hTrm4; Misu; mRNA cytosine C(5)-methyltransferase; MRT5; Myc-induced SUN domain containing protein; myc-induced SUN domain-containing protein; Myc-induced SUN-domain-containing protein; NOL1/NOP2/Sun domain family 2; NOL1/NOP2/Sun domain family member 2; NOL1/NOP2/Sun domain family, member 2; NOP2/Sun domain family, member 2; NOP2/Sun RNA methyltransferase family member 2; NOP2/Sun RNA methyltransferase family, member 2; Nsun2; RGD1311954; RNA cytosine C(5)-methyltransferase NSUN2; SAKI; substrate of AIM1/Aurora kinase B; TRM4; tRNA (cytosine(34)-C(5))-methyltransferase; tRNA (cytosine-5-)-methyltransferase NSUN2; tRNA cytosine C(5)-methyltransferase; tRNA methyltransferase 4 homolog
Gene Symbols NSUN2
Host Species Rabbit
Immunogen Recombinant protein within human NSUN2 aa 1-767.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 0, 28114, 54888
Target Species Human, Mouse, Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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