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Invitrogen™ NTAL Polyclonal Antibody
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Catalog No. 01676757
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100 μg
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Catalog No. Quantity
01-676-757 100 μg
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Catalog No. 01-676-757 Supplier Invitrogen™ Supplier No. PA119441
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Description

Rabbit Polyclonal Antibody

This antibody recognizes N-terminal cytoplasmic domain of mouse Non-T cell Activation Linker (NTAL), also known as LAB (linker of activated B cells), a 25 kDa transmembrane adaptor protein present in membrane microdomains (rafts) of B cells, NK cells and myeloid cells. Western Blot: non-reducing conditions.

NTAL (Non-T cell Activation Linker), also known as LAB (Linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NTAL
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.4
Gene LAT2
Gene Accession No. Q9JHL0
Gene Alias AW125574; HSPC046; LAB; Lat2; LAT-2 like; Linker for activation of B-cells; linker for activation of T cells family, member 2; linker for activation of T cells, transmembrane adaptor 2; linker for activation of T-cells family member 2; Membrane-associated adapter molecule; non-T cell activation linker; non-T-cell activation linker; NTAL; WBS15; WBSCR15; WBSCR5; Williams-Beuren syndrome chromosomal region 15 protein; williams-Beuren syndrome chromosomal region 15 protein homolog; Williams-Beuren syndrome chromosomal region 5 protein; Williams-Beuren syndrome chromosome region 5 homolog; Williams-Beuren syndrome chromosome region 5-like protein; WSCR5
Gene Symbols LAT2
Host Species Rabbit
Immunogen Recombinant N-terminal cytoplasmic domain (aa 124-203) of mouse NTAL.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56743
Target Species Mouse
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG
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