Invitrogen™ NTE Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101720

Catalog No. PIPA5101720

Description

Antibody detects endogenous levels of total PNPLA6.

This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: NTE
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: pnpla6
• Gene Alias: 5'-NT; 5'-nucleotidase; 5'-nucleotidase ecto; 5'-nucleotidase, ecto (CD73); AI661849; BNHS; CALJA; CD73; E5NT; ecto-5'-nucleotidase; eN; eNT; iPLA2delta; LNMS; MSws; Neuropathy target esterase; NT; NT5; NT5E; NTE; NTEMND; OMCS; patatin like phospholipase domain containing 6; patatin-like phospholipase domain containing 6; patatin-like phospholipase domain-containing protein 6; PNPLA6; Purine 5-Prime-Nucleotidase; RGD1564611; SPG39; Swiss cheese; Swiss-cheese; sws; wu:fy20f06
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10908, 50767
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q3TRM4, Q8IY17
• Gene Symbols: pnpla6
• Immunogen: A synthesized peptide derived from human PNPLA6(Accession Q8IY17), corresponding to amino acid residues L326-R376.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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