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Invitrogen™ Human NUAK2, GST Tag Recombinant Protein

Catalog No. PV6377
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PV6377 100 μg
PV6376 10 μg
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Catalog No. PV6377 Supplier Invitrogen™ Supplier No. PV6377
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Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Recombinant full-length human NUAK2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. Validated in LanthaScreen™ Kinase Binding Assay Protocols available for simple use and optimized performance Multiple pack sizes available for convenient use Related Product:LanthaScreen™ Eu Kinase Binding Assay Protein Form: Recombinant The gene accession number for NUAK2 is NP_112214.1.

NUAK2 or SNF1/AMP kinase-related kinase (SNARK) is a member of the NUAK family of SNF1-like kinase 2. NUAK2 is activated by muscle contraction and is a unique mediator of contraction-stimulated glucose transport in skeletal muscle (1). NUAK2 is involved in cellular stress responses linked to obesity and type 2 diabetes. NUAK2 shows kinase activity against a synthetic test peptide and the activity in keratinocytes is increased by AMP and 5-amino-4-imidazolecarboxamide riboside, implying that AMPK kinase-dependent pathway can activate NAUK2. Glucose deprivation also increases NAUK2 activity in baby hamster kidney fibroblasts.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9H093
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50mM tris HCl with 0.25mM DTT, 0.1mM EDTA, 25% glycerol, 0.1mM PMSF, 10mM glutathione, 150mM NaCl and no preservative; pH 7.5
Gene ID (Entrez) 81788
Molecular Weight (g/mol) 96.3 kDa
Name Human NUAK2, GST Tag
pH Range 7.5
Purification Method Purified
Quantity 100 μg
Storage Requirements -80°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias 1200013B22Rik; EMBL:AAH81899.1}; mKIAA0537; NUAK family kinase 2; NUAK family SNF1-like kinase 2; NUAK family, SNF1-like kinase, 2; NUAK2; nuak2 {ECO:0000312; Omphalocele kinase 2; Omphk2; SNARK; SNF1/AMP activated protein kinase; SNF1/AMP kinase-related kinase; SNF1/AMP-activated protein kinase; UV126
Common Name NUAK2
Gene Symbol Nuak2
Protein Length 1-628
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag GST-tag
Sequence 1-628
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Kinase Group Serine/Threonine Kinase
Expression System Baculovirus
Protein Family Kinases & Inhibitors
Protein Form Recombinant, Full Length
Form Liquid
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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