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NUDT15 Monoclonal Antibody (OTI4B9), TrueMAB™, OriGene
SDP

Catalog No. 501684068
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100 μL
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50-168-4068 100 μL
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Catalog No. 50-168-4068 Supplier OriGene Supplier No. TA811479
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Description

Mouse Monoclonal Antibody

Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear. May have a role in DNA synthesis and cell cycle progression throught the interaction with PCNA.

Specifications

Antigen NUDT15
Applications Western Blot
Classification Monoclonal
Clone OTI4B9
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene NUDT15
Gene Accession No. Q9NV35
Gene Alias MTH2, NUDT15D
Gene Symbols NUDT15
Host Species Mouse
Immunogen Full length human recombit protein of human NUDT15 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55270
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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