NUDT15 Monoclonal Antibody (OTI4B9), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA811479

Catalog No. 50-168-4068

Description

Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear. May have a role in DNA synthesis and cell cycle progression throught the interaction with PCNA.

Specifications

• Antigen: NUDT15
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q9NV35
• Gene Symbols: NUDT15
• Immunogen: Full length human recombit protein of human NUDT15 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI4B9
• Conjugate: Unconjugated
• Gene: NUDT15
• Gene Alias: MTH2, NUDT15D
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55270
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid