NuMA Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA587448

Catalog No. PIPA587448

Description

Immunogen sequence: MTLHATRGAA LLSWVNSLHV ADPVEAVLQL QDCSIFIKII DRIHGTEEGQ QILKQPVSER LDFVCSFLQK NRKHPSSPEC LVSAQKVLEG SELELAKMTM LLLYHSTMSS KSPRDWEQFE YKIQAELAVI LKFVLDHEDG LNLNEDLENF LQKAPVPSTC SSTFPEELSP PSHQAKREIR FLELQKVASS SSGNNFLSGS PASPMGDILQ TPQFQMRRLK KQLADERSNR DELELELAEN RKLLTEKDAQ IAMMQQRIDR LALLNEKQAA SPLEPKELEE LRDKNESLTM RLHETLKQCQ DLKTEKSQM; Positive Samples: HeLa, Mouse kidney; Cellular Location: Chromosome, Cytoplasm, Nucleus matrix, cytoskeleton, spindle pole

NuMA (nuclear mitotic apparatus) is a long coil-coiled protein that plays a role in the interphase and mitosis phases of a cell cycle. In interphase, it has been hypothesized to play a structural role in the nucleoskeleton that may be important in nuclear organization and functions. During mitosis, it is associated with spindle microtubule organization and chromosome positioning.

Specifications

• Antigen: NuMA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NUMA1
• Gene Alias: 6720401E04Rik, AA764025, AL022610, AU014979, centrophilin stabilizes mitotic spindle in mitotic cells, NMP22, NMP-22, Nuclear matrix protein-22, Nuclear mitotic apparatus protein, Nuclear mitotic apparatus protein 1, NUMA, NuMA protein, Numa1, SP-H antigen, structural nuclear protein
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 101706, 308870, 4926
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.78 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
• Gene Accession No.: E9Q7G0, Q14980
• Gene Symbols: NUMA1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-309 of human NUMA1 (NP_0061762)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG