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Invitrogen™ NUP107 Monoclonal Antibody (39C7)
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Catalog No. 01670288
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500 μL
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Catalog No. Quantity
01-670-288 500 μL
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Catalog No. 01-670-288 Supplier Invitrogen™ Supplier No. MA110031
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Description

Mouse Monoclonal Antibody

For immunofluorescence on yeast cells, try MCA-39C7 diluted 1:100 to 1:500. For immunofluorescence on mammalian cells try at 1:50 to 1:100.

The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-107 is part of the hetero-oligomeric complex that also contains NUP160, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP107 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP107 may be an important drug target in HIV treatment. Multiple isoforms of NUP107 are known to exist.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NUP107
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 39C7
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Tissue culture supernatant with 5mM sodium azide
Gene NUP107
Gene Accession No. P52590, P57740, Q10331, Q8BH74, Q9V466
Gene Alias 107 kDa nucleoporin; AW541137; BcDNA.LD18761; BcDNA:LD18761; C76801; CG6743; CG6743-PA; Dmel\CG6743; Dmel_CG6743; dmNup107; NPHS11; nuclear pore complex; Nuclear pore complex protein Nup107; Nuclear pore complex protein Nup107-like protein; nucleoporin 107; Nucleoporin 107kD; nucleoporin 107kDa; nucleoporin Nup107; Nup; Nup 107; nup107; Nup107-PA; Nup170; NUP84; p105
Gene Symbols NUP107
Host Species Mouse
Immunogen Yeast nuclear preparation.
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100059287, 100516909, 101751988, 103468, 116555, 3361255, 34481, 504823, 57122
Target Species Bovine, Chicken, Drosophila, Horse, Human, Mouse, Pig, Rat, Yeast
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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