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NUP50 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. p-7210006 Shop All Proteintech Group Inc Products
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50-173-3091 150 μL
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Catalog No. 50-173-3091 Supplier Proteintech Group Inc Supplier No. 207981AP150UL
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Description

Rabbit Polyclonal Antibody

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. NUP50 is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. NUP50 may serve as a binding site on the nuclear side of the pore complex for export receptor-cargo complexes. It interacts with multiple transport receptor proteins including p27Kip1. This interaction is required for correct intracellular transport and degradation of p27Kip1.

Specifications

Antigen NUP50
Applications Western Blot
Classification Polyclonal
Concentration 0.57 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene NUP50
Gene Accession No. O08587, Q9JIH2, Q9UKX7
Gene Alias 50 kDa nucleoporin, nucleoporin 50kDa, Nucleoporin Nup50, NUP50
Gene Symbols Nup50
Host Species Rabbit
Immunogen NUP50 Fusion Protein Ag14710
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10762, 18141, 25497
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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