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Invitrogen™ NUP88 Polyclonal Antibody
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Catalog No. PIPA5103980
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100 μL
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PIPA5103980 100 μL
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Catalog No. PIPA5103980 Supplier Invitrogen™ Supplier No. PA5103980
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total NUP88.

The nuclear pore complex (NPC) mediates bidirectional macromolecular traffic between the nucleus and cytoplasm in eukaryotic cells and is comprised of more than 100 different subunits. Many of the subunits belong to a family called nucleoporins (Nups), which are characterized by the presence of O-linked-N-acetylglucosamine moieties and a distinctive pentapeptide repeat (XFXFG). Nup88 (nucleoporin 88 kDa) is a 741 amino acid protein that localizes to the nucleus and functions as an essential component of the nuclear pore complex. Expressed ubiquitously, Nup88 is subject to phosphorylation by ATM or ATR and is upregulated in malignant neoplasms and precancerous dysplasias, suggesting a role in tumorigenesis. The gene encoding Nup88 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1, 200 genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NUP88
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene NUP88
Gene Accession No. Q8CEC0, Q99567
Gene Alias 88 kDa nuclear pore complex protein; 88 kDa nucleoporin; karyoporin; nuclear pore complex protein 88; nuclear pore complex protein Nup88; nucleoporin 88; nucleoporin 88kDa; nucleoporin Nup84; Nucleoporin Nup88; Nup84; NUP88; Prei2; preimplantation protein 2
Gene Symbols NUP88
Host Species Rabbit
Immunogen A synthesized peptide derived from human NUP88(Accession Q99567), corresponding to amino acid residues D436-T486.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19069, 4927
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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