Invitrogen™ NUS1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA555638

Catalog No. PIPA555638

Description

Immunogen sequence: ASLLSSNGCP DPDLVLKFGP VDSTLGFLPW HIRLTEIVSL PSHLNISYED FFSALRQYAA CEQRLGK Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 90%.

With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator.

Specifications

• Antigen: NUS1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NUS1
• Gene Alias: 1600027K07Rik; AU019165; AW538011; BC003223; C6orf68; Cis-prenyltransferase subunit NgBR; D10Ertd438e; dehydrodolichyl diphosphate syntase complex subunit NUS1; dehydrodolichyl diphosphate syntase complex subunit NUS1 pseudogene; dehydrodolichyl diphosphate synthase complex subunit NUS1; di-trans,poly-cis-decaprenylcistransferase; MGC:7199; NgBR; Nogo-B receptor; Nuclear undecaprenyl pyrophosphate synthase 1 homolog; nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae); Nus1; NUS1 dehydrodolichyl diphosphate synthase subunit; NUS1, dehydrodolichyl diphosphate synthase subunit; RGD1307879; TANGO14; transport and golgi organization 14 homolog
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116150
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96E22
• Gene Symbols: NUS1
• Immunogen: Recombinant protein corresponding to Human NUS1. Recombinant protein control fragment (Product #RP-94908).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG