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Invitrogen™ NXF3 Polyclonal Antibody
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Catalog No. PIPA530700
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100 μL
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PIPA530700 100 μL
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Catalog No. PIPA530700 Supplier Invitrogen™ Supplier No. PA530700
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7. Predicted reactivity: Chimpanzee (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NXF3
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.95 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene NXF3
Gene Accession No. Q9H4D5
Gene Alias Nuclear RNA export factor 3; NXF3; RGD1564923; TAPL3; TAPL-3; TAP-like protein 3
Gene Symbols NXF3
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human NXF3. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56000
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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