O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 98%

Description

CAS: 94790-37-1 | C11H16F6N5OP | 379.247 g/mol

O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate is used as a coupling reagent for solid-phase peptide synthesis. It has been shown to effectively suppress racemization.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
O-(1H-Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate is used as a coupling reagent for solid-phase peptide synthesis. It has been shown to effectively suppress racemization.

Solubility
Soluble in acetonitrile.

Notes
Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 94790-37-1
• Molecular Formula: C11H16F6N5OP
• Molecular Weight (g/mol): 379.247
• MDL Number: MFCD00075445
• InChI Key: UQYZFNUUOSSNKT-UHFFFAOYSA-N
• Synonym: hbtu, o-benzotriazol-1-yl-n,n,n',n'-tetramethyluronium hexafluorophosphate, 2-1h-benzotriazole-1-yl-1,1,3,3-tetramethyluronium hexafluorophosphate, hbtu-reagent, o-benzotriazol-1-yl-tetramethyluronium hexafluorophosphate, hbtu o-benzotriazole-n,n,n',n'-tetramethyl-uronium-hexafluoro-phosphate, n,n,n',n'-tetramethyl-o-1h-benzotriazol-1-yl uronium hexafluorophosphate, o-1h-benzotriazol-1-yl-n,n,n',n'-tetramethyluronium hexafluorophosphate, o-benzotriazole-n,n,n',n'-tetramethyluronium hexafluorophosphate
• PubChem CID: 2733084
• IUPAC Name: [benzotriazol-1-yloxy(dimethylamino)methylidene]-dimethylazanium;hexafluorophosphate
• SMILES: CN(C)C(=[N+](C)C)ON1C2=CC=CC=C2N=N1.F[P-](F)(F)(F)(F)F

• Melting Point: ∼200°C (decomposition)
• Quantity: 100 g
• Beilstein: 7328329
• Solubility Information: Soluble in acetonitrile.
• Formula Weight: 379.25
• Percent Purity: 98%
• Chemical Name or Material: O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	423-020-5
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only