O-Acetylsalicyloyl chloride, 97%

Description

CAS: 5538-51-2 | C9H7ClO3 | 198.602 g/mol

O-Acetylsalicyloyl chloride was used in the synthesis of enantiomerically pure bidentate heteroorganic ligands built on simple achiral skeletons and containing an aziridine moiety. It was used in the general synthesis of acetoxybenzamides. It was used in the chemical synthesis of 2,2,6,6-tetramethyl-1-piperidinyloxy(TEMPO)-aspirin conjugate via condensation reaction with 4-hydroxy-TEMPO. It was used as reagent in acylation of cyclobutenediones.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
O-Acetylsalicyloyl chloride was used in the synthesis of enantiomerically pure bidentate heteroorganic ligands built on simple achiral skeletons and containing an aziridine moiety. It was used in the general synthesis of acetoxybenzamides. It was used in the chemical synthesis of 2,2,6,6-tetramethyl-1-piperidinyloxy(TEMPO)-aspirin conjugate via condensation reaction with 4-hydroxy-TEMPO. It was used as reagent in acylation of cyclobutenediones.

Solubility
Soluble in toluene. Reacts with water.

Notes
Moisture Sensitive. Store under dry inert gas. Store away from strong bases.

Specifications

Chemical Identifiers

• CAS: 5538-51-2
• Molecular Formula: C9H7ClO3
• Molecular Weight (g/mol): 198.602
• MDL Number: MFCD00000663
• InChI Key: DSGKWFGEUBCEIE-UHFFFAOYSA-N
• Synonym: 2-acetoxybenzoyl chloride, o-acetylsalicyloyl chloride, acetylsalicyloyl chloride, 2-chlorocarbonyl phenyl acetate, benzoyl chloride, 2-acetyloxy, aspirin chloride, o-acetylsalicyloylchloride, acetylsalicoyl chloride, 2-carbonochloridoyl phenyl acetate, ascc
• PubChem CID: 79668
• IUPAC Name: (2-carbonochloridoylphenyl) acetate
• SMILES: CC(=O)OC1=CC=CC=C1C(=O)Cl

• Melting Point: 47°C to 50°C
• Boiling Point: 134°C to 136°C (12 mmHg)
• Flash Point: >110°C (230°F)
• Odor: Pungent, Makes Eyes Water
• Quantity: 25 g
• UN Number: UN3261
• Beilstein: 880372
• Sensitivity: Moisture sensitive
• Solubility Information: Soluble in toluene. Reacts with water.
• Formula Weight: 198.61
• Percent Purity: 97%
• Chemical Name or Material: O-Acetylsalicyloyl chloride

Safety and Handling

Hazard Category	H302-H314
Hazard Statement	GHS H Statement H314-H318-H302 Causes severe skin burns and eye damage. Causes serious eye damage. Harmful if swallowed.
Precautionary Statement	P260-P264b-P270-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S.
EINECSNumber	226-899-1
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only