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Sigma Aldrich Fine Chemicals Biosciences MS PhosphoMix 1 Light Phos
Supplier: Sigma Aldrich Fine Chemicals Biosciences MSP1L5X1VL
The MS PhosphoMix line of products allows for the testing of the strengths and weaknesses of phosphopeptide sample processing mass spectrometry analysis and instrument configurations. The mixes are produced from synthetic phosphopeptides with sequences derived from naturally occurring peptides as identified by Mann et al. in HeLa cells. Because the sequences are derived from mammalian cells many natural phosphorylation motifs such as those that present an abundance of proline are represented. Additionally the phosphopeptide distribution in each mix has been chosen to present a broad range of characteristics including ionizability LC retention time charge state and isoelectric point. finally PhosphoMix-1 2 and 3 were designed in a complementary fashion as highlighted on the following page. for example all three mixes contain peptides of the same sequence with different sites of phosphorylation.Each of the three phosphopeptides mixes are available in their naturally occurri
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