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Tocris™ OD 36 hydrochloride

Catalog No. 659810
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Catalog No. Quantity
65-981-0 10 mg
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Catalog No. 65-981-0 Supplier Tocris™ Supplier No. 6598/10
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Description

Potent RIP2 kinase inhibitor

OD 36 hydrochloride is a potent receptor-interacting protein kinase 2 (RIPK2) inhibitor (IC50 = 5.3 nM). Displays similar % inhibition against ALK-2 and SIK2 at 100 nM. Downregulates expression of a panel of RIPK2-dependent genes. Inhibits recruitment of inflammatory cells in a mouse MDP-induced peritonitis model.

Specifications

Chemical Name or Material 6-Chloro-10,11,14,17-tetrahydro-13H-1,16-etheno-4,8-metheno-1H-pyrazolo[3,4-g][1,14,4,6]dioxadiazacyclohexadecine hydrochloride
CAS 1638644-62-8
Quantity 10 mg
Molecular Formula C16H15ClN4O2.HCl
Formula Weight 367.23
Product Type Inhibitor
Purity 98%
Product Title
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