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Invitrogen™ Omega-hexatoxin-Hv1a Polyclonal Antibody
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Catalog No. FEPA5144389
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FEPA5144389 100 μL
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Catalog No. FEPA5144389 Supplier Invitrogen™ Supplier No. PA5144389
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Rabbit Polyclonal Antibody

Omega-hexatoxin-Hv1a Polyclonal Antibody for Western Blot, ELISA

Reversibly and voltage-independently blocks both mid-low- (M-LVA) and high-voltage-activated (HVA) calcium channels in cockroach DUM neurons (PubMed:17610847). Is lethal to many insect species but not toxic to mammals (PubMed:9228949, PubMed:16779650). May target the insect high-voltage-activated calcium channel Dmca1D. Also inhibits acarines calcium channels. An extremely high toxin concentration partially inhibits Cav1.2/CACNA1C, Cav2.1/CACNA1A and Cav2.2/CACNA1B calcium channel of rats. As for omega-AcTx-Hv2a, the phenotypic effect of injection of this toxin into lone star ticks (Amblyomma americanum) is curling of all eight legs into closed loops.
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Specifications

Antigen Omega-hexatoxin-Hv1a
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 4 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4
Gene Alias Omega-hexatoxin-Hv1a
Host Species Rabbit
Immunogen Recombinant Hadronyche versuta Omega-hexatoxin-Hv1a protein (1-37aa ).
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Arthropod
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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