Invitrogen™ Omega-hexatoxin-Hv1a Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5144389

Catalog No. FEPA5144389

Description

Omega-hexatoxin-Hv1a Polyclonal Antibody for Western Blot, ELISA

Reversibly and voltage-independently blocks both mid-low- (M-LVA) and high-voltage-activated (HVA) calcium channels in cockroach DUM neurons (PubMed:17610847). Is lethal to many insect species but not toxic to mammals (PubMed:9228949, PubMed:16779650). May target the insect high-voltage-activated calcium channel Dmca1D. Also inhibits acarines calcium channels. An extremely high toxin concentration partially inhibits Cav1.2/CACNA1C, Cav2.1/CACNA1A and Cav2.2/CACNA1B calcium channel of rats. As for omega-AcTx-Hv2a, the phenotypic effect of injection of this toxin into lone star ticks (Amblyomma americanum) is curling of all eight legs into closed loops.

Specifications

• Antigen: Omega-hexatoxin-Hv1a
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Alias: Omega-hexatoxin-Hv1a
• Immunogen: Recombinant Hadronyche versuta Omega-hexatoxin-Hv1a protein (1-37aa ).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 4 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Target Species: Arthropod
• Product Type: Antibody
• Isotype: IgG