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Invitrogen™ OPRL1 Polyclonal Antibody
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Catalog No. PIPA570443
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100 μL
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PIPA570443 100 μL
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Catalog No. PIPA570443 Supplier Invitrogen™ Supplier No. PA570443
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Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%.

The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. The nociceptin receptor is a G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OPRL1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene Oprl1
Gene Accession No. P41146
Gene Alias K3 opiate receptor; kappa3-related opioid receptor; kappa-type 3 opioid receptor; KOR3; KOR-3; LC132; LC132 Receptor-Like; morc; MOR-C; N/OFQ receptor; nociceptin receptor; nociceptin receptor ORL1; nociceptin/ orphaninFQ receptor; nociceptin/orphanin FQ receptor; NOCIR; nop; NOPr; OFQR; OOR; opiate receptor-like 1; opioid receptor-like 1; opioid receptor-like protein Zf-orl; opioid related nociceptin receptor 1; opioid-receptor-like protein; OPPRL1; oprl; Oprl1; ORGC; ORL1; orphanin FQ receptor; orphanin FQ receptor-a; orphanin FQ receptor-b; orphanin FQ receptor-e; peptide receptor; ROR-C; seven transmembrane G protein-coupled receptor; XOR; XOR1
Gene Symbols Oprl1
Host Species Rabbit
Immunogen synthetic peptide directed towards the middle region of human OPRL1.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4987
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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