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OPTN Monoclonal Antibody (OTI7H2), TrueMAB™, OriGene
SDP

Catalog No. 501684422
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Catalog No. Quantity
50-168-4422 100 μL
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Catalog No. 50-168-4422 Supplier OriGene Supplier No. TA812132
May include imposed supplier surcharges.
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Mouse Monoclonal Antibody

This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.

Specifications

Antigen OPTN
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI7H2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene OPTN
Gene Accession No. Q96CV9
Gene Alias ALS12, FIP2, GLC1E, HIP7, HYPL, NRP, TFIIIA-INTP
Gene Symbols OPTN
Host Species Mouse
Immunogen Full length human recombit protein of human OPTN produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10133
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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