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Invitrogen™ ORAI2 Polyclonal Antibody
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Catalog No. PIPA531788
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100 μL
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PIPA531788 100 μL
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Catalog No. PIPA531788 Supplier Invitrogen™ Supplier No. PA531788
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: H1299. Predicted reactivity: Mouse (94%), Rat (94%), Zebrafish (80%), Chicken (88%), Rhesus Monkey (99%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ORAI2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene ORAI2
Gene Accession No. Q8BH10, Q96SN7
Gene Alias A730041O15Rik; C7orf19; calcium release-activated calcium channel 2; calcium release-activated calcium modulator 2 protein; CAP-binding protein complex interacting protein 2; CAP-binding protein complex-interacting protein 2; CBCIP2; H_NH0514P08.8; MEM142B; ORAI calcium release-activated calcium modulator 2; ORAI2; PP1729; Protein orai-2; putative protein ORAI2-2; RGD1310213; TMEM142B; Transmembrane protein 142B
Gene Symbols ORAI2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human ORAI2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 269717, 304592, 80228
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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