ORC6 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A301493A

Catalog No. 50-156-0531

Description

The recommended shelf life for this product is 1 year from date of receipt.

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. It has been shown that this protein and and ORC1L are loosely associated with the core complex consisting of ORC2L, -3L, -4L and -5L. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.

Specifications

• Antigen: ORC6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ORC6
• Gene Alias: ORC6L; origin recognition complex, subunit 6 homolog-like (yeast); ORC6; origin recognition complex subunit 6; origin recognition complex, subunit 6-like (yeast); origin recognition complex, subunit 6 (yeast homolog)-like
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23594
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 1 mg/ml
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene Accession No.: Q9Y5N6
• Gene Symbols: ORC6
• Immunogen: Between 230 and 252
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG