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Invitrogen™ ORM2 Monoclonal Antibody (D1), Invitrogen™

Catalog No. p-7240874
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Quantity:
20 μL
100 μL
Catalog No. Quantity
PIMA543637 20 μL
PIMA543636 100 μL
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Catalog No. PIMA543637

Supplier: Invitrogen™ MA543637

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Description

Mouse Monoclonal Antibody

AGP (a 1-acid Glycoprotein) is an acute phase plasma protein synthesized by the liver. It functions to regulate the interaction between blood cells and endothelial cells, and together with haptoglobin and C reactive protein, it also mediates the extravasation of cells during infection and inflammation. Expression of AGP is induced by acute-phase stimulatory agents such as bacterial lipopolysaccharides. AGP has a high affinity, low capacity binding for basic drugs at physiological pH. In human plasma, AGP is found at levels of 0.5-1.4 mg/mL, though this is elevated during acute inflammation, and, as a result, levels of this protein can be used to diagnose inflammatory conditions. Multiple AGP genes exist, including AGP-1, AGP-2, AGP-3 and AGP-8. AGP-1 and AGP-2 contain five and six potential N-glycosylation sites, respectively. Abnormal expression of the APG-1 gene is linked to sarcoidosis and other immunogenetic diseases, while mutations in the APG-2 gene are associated with different types of carcinomas.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ORM2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone D7
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene ORM2
Gene Accession No. P19652
Gene Alias AGP 2; Agp1; AGP2; Agp-2; AGP-B; AGP-B'; alpha-1-acid glycoprotein 1; alpha-1-acid glycoprotein 2; alpha-1-acid glycoprotein, type 2; bM340H1.5 (orosomucoid 2); OMD 2; OMD2; ORM2; Orm-2; orosomucoid 2; Orosomucoid2; orosomucoid-2
Gene Symbols ORM2
Host Species Mouse
Immunogen Gln19-Ser201 (Accession P19652), with N-terminal His Tag.
Purification Method Protein A/G
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5005
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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