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Invitrogen™ OSMR Polyclonal Antibody
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Catalog No. PIPA547857
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100 μg
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PIPA547857 100 μg
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Catalog No. PIPA547857 Supplier Invitrogen™ Supplier No. PA547857
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Description

Goat Polyclonal Antibody

Reconstitute at 0.2 mg/mL in sterile PBS.

Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF.Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OSMR
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene OSMR
Gene Accession No. O70458
Gene Alias IL-31 receptor subunit beta; IL-31R subunit beta; IL-31RB; IL-31R-beta; interleukin-31 receptor subunit beta; MGC150626; MGC150627; MGC75127; oncostatin M receptor; oncostatin receptor; oncostatin-M specific receptor beta subunit; oncostatin-M specific receptor subunit beta; oncostatin-M-specific receptor subunit beta; OSMR; Osmrb; PLCA1
Gene Symbols OSMR
Host Species Goat
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse OSM R beta Glu24-Leu738.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18414
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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