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Tocris Bioscience™ OSU 03012
GREENER_CHOICE

Catalog No. 568250
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

PDPK1 (PDK1) inhibitor; inhibits Akt signaling

OSU 03012 is a PDPK1 (PDK1) inhibitor; inhibits Akt signaling. Induces apoptosis of PC-3 and medulloblastoma cells, and inhibits growth of a number of tumor cell lines. Sensitizes radiotherapy-induced cell death and enhances cytotoxic effects of chemotherapeutic agents in vitro. Attenuates tumor growth of medulloblastoma xenografts in mice.

Specifications

Chemical Name or Material 2-Amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]acetamide
CAS 742112-33-0
Quantity 50 mg
Target PDK-1 Inhibitors
Molecular Formula C26H19F3N4O
Formula Weight 460.45
Purity >98%
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