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Tocris Bioscience™ OSU 03012

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Quantity:
10 mg
50 mg
Description
OSU 03012 is a PDPK1 (PDK1) inhibitor; inhibits Akt signaling. Induces apoptosis of PC-3 and medulloblastoma cells, and inhibits growth of a number of tumor cell lines. Sensitizes radiotherapy-induced cell death and enhances cytotoxic effects of chemotherapeutic agents in vitro. Attenuates tumor growth of medulloblastoma xenografts in mice.
Specifications
Specifications
Chemical Name or Material | 2-Amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]acetamide |
CAS | 742112-33-0 |
Quantity | 50 mg |
Target | PDK-1 Inhibitors |
Molecular Formula | C26H19F3N4O |
Formula Weight | 460.45 |
Purity | >98% |
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