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Description
Recommended positive controls: A431, HepG2, mouse Liver. Predicted reactivity: Mouse (94%), Rat (93%), Pig (94%), Chicken (80%), Bovine (94%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
Specifications
Specifications
| Antigen | OTC |
| Applications | Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.65 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 20% glycerol and 0.025% ProClin 300; pH 7 |
| Gene | OTC |
| Gene Accession No. | P00480, P11725 |
| Gene Alias | AI265390; OCTD; ornithine carbamoyltransferase; ornithine carbamoyltransferase, mitochondrial; Ornithine transcarbamylase; Otc; OTCase; Sf; sparse fur; spf |
| Gene Symbols | OTC |
| Show More |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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