Invitrogen™ OTC Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5119764

Catalog No. PIPA5119764

Description

Positive Control: Rat colon tissue lysate, human liver tissue lysate, mouse liver tissue lysate, SW480, human liver carcinoma tissue, human liver tissue. Subcellular Location: Mitochondrion.

This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.

Specifications

• Antigen: OTC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: OTC
• Gene Alias: AI265390; OCTD; ornithine carbamoyltransferase; ornithine carbamoyltransferase, mitochondrial; Ornithine transcarbamylase; Otc; OTCase; Sf; sparse fur; spf
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18416, 25611, 5009
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P00480, P00481, P11725
• Gene Symbols: OTC
• Immunogen: Recombinant protein within human OTC/Ornithine Carbamoyltransferase aa 200-354.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov