Invitrogen™ OTX2 Recombinant Rabbit Monoclonal Antibody (14H14L5)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ 701948

Catalog No. 70-194-8

Description

This antibody is predicted to react with Rat, Mouse, Pig and Sheep. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

OTX2 is a 289 amino acid containing protein encoding a member of the bicoid sub-family of homeodomain-containing transcription factors. It has two known alternative splice variants with distinct isoforms though presence of other isoforms cannot be excluded. The protein is an early marker of endodermal differentiation of embryonic stem cells and may play a role in the development of the brain and the sensory organs. The proteinmay bind to BCD target sequence (BTS): 5-'TCTAATCCC-3'. Defects in OTX2 are the cause of microphthalmia syndromic type 5 (MCOPS5).

Specifications

• Antigen: OTX2
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.2
• Gene Accession No.: P32243, P80206, Q64201
• Gene Symbols: OTX2
• Immunogen: Peptides corresponding to Human OTX2 (aa 20-39, 276-289).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot, Immunocytochemistry
• Clone: 14H14L5
• Conjugate: Unconjugated
• Gene: OTX2
• Gene Alias: CPHD6; E130306E05Rik; homeobox Otx2; homeobox protein OTX2; MCOPS5; orthodenticle homeobox 2; orthodenticle homolog 2; OTX; OTX2
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 18424, 305858, 5015
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid