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Tocris Bioscience™ OXF BD 02

Catalog No. 492850
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Catalog No. Quantity
49-285-0 50 mg
49-281-0 10 mg
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Catalog No. 49-285-0 Supplier Tocris Bioscience™ Supplier No. 4928/50
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Description

Selective BRD4(1) inhibitor

OXF BD 02 is a selective inhibitor of the first bromodomain of BRD4 (BRD4(1)) (IC50 = 382 nM). Exhibits 2-3-fold selectivity for BRD4(1) over the CBP bromodomain and has little affinity for a range of other bromodomains. Reduces viability of lung adenocarcinoma cell lines and attenuates proliferation of MV-4-11 leukemia cells. Cell permeable.

Specifications

Purity >98%
Quantity 50 mg
Product Type OXF BD 02
Molecular Weight (g/mol) 295.33
Inhibitors OXF BD 02

For Research Use Only

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