Tocris Bioscience™ P-3FAX-Neu5Ac

Description

Sialic acid analog; sialyltransferase inhibitor

P-3FAX-Neu5Ac is a cell-permeable sialic acid analog. Deacetylation occurs intracellularly giving rise to a sialyltransferase inhibitor. Abolishes expression of SLex expression on HL-60 cells and reduces E-selectin and P-selectin binding. Prevents metastasis formation in a mouse lung metastasis model.

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Specifications

• Chemical Name or Material: 5-(acetylamino)-3,5-dideoxy-3-fluoro-D-erythro-α-L-manno-2-nonulopyranosonic acid methyl ester 2,4,7,8,9-pentaacetate
• CAS: 117405-58-0
• Quantity: 10 mg
• Target: Other Transferase Inhibitors
• Molecular Formula: C₂₂H₃₀FNO₁₄
• Formula Weight: 551.47
• Purity: >97%