p-Toluenesulfonyl fluoride, 98%

Description

CAS: 455-16-3 | C7H7FO2S | 174.189 g/mol

p-Toluenesulfonyl fluoride is used for sulfonylation of organometallic reagents as a simple, one-step synthesis of sulfones. It is useful in the treatment of Alzheimer?s disease. It is used to study the DNS polymerase from spinach leaf extracts. It was used in isolation and separation of Pseudomonas aeruginosa membranes by density sucrose gradient centrifugation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Hydrolyzes in water.

Notes
Moisture Sensitive. Incompatible with bases, moisture and oxidizing agents. Store under dry inert gas. Protect from humidity and water.

Specifications

Chemical Identifiers

• CAS: 455-16-3
• Molecular Formula: C7H7FO2S
• Molecular Weight (g/mol): 174.189
• MDL Number: MFCD00007421
• InChI Key: IZZYABADQVQHLC-UHFFFAOYSA-N
• Synonym: p-toluenesulfonyl fluoride, tosyl fluoride, 4-toluenesulfonyl fluoride, benzenesulfonyl fluoride, 4-methyl, 4-tolylsulfonyl fluoride, toluene-4-sulfonyl fluoride, p-methylbenzenesulfonyl fluoride, p-toluenesulphonyl fluoride, toluene-p-sulphonyl fluoride, p-methylphenylsulfonyl fluoride
• PubChem CID: 9965
• IUPAC Name: 4-methylbenzenesulfonyl fluoride
• SMILES: CC1=CC=C(C=C1)S(=O)(=O)F

• Melting Point: 40°C to 41°C
• Boiling Point: 112°C (16 mmHg)
• Flash Point: 105°C (221°F)
• Quantity: 25 g
• UN Number: UN3261
• Beilstein: 2208423
• Sensitivity: Moisture sensitive
• Solubility Information: Hydrolyzes in water.
• Formula Weight: 174.19
• Percent Purity: 98%
• Chemical Name or Material: p-Toluenesulfonyl fluoride

Safety and Handling

Hazard Category	H302+H312+H332-H314
Hazard Statement	GHS H Statement H301-H314-H318 Toxic if swallowed. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statement	P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S.
EINECSNumber	207-238-6
RTECSNumber	XT8050000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only