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p107 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

$518.60

Specifications

Antigen p107
Concentration 0.37 mg/mL
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-560-388
SDP
Encompass_Preferred
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Proteintech Group Inc
133541AP150UL
150 μL
Each of 1 for $518.60
Only null left
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Description

Description

RB-like 1 is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and RB-like 1 can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that RB-like 1 may also be a tumor suppressor.
Specifications

Specifications

p107
Immunoprecipitation, Western Blot
Unconjugated
Rabbit
Human, Mouse, Rat
P28749, Q64701
19650, 5933, 680111
p107 Fusion Protein Ag4146
Primary
-20°C
RBL1
0.37 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
CP107, p107, PRB1, RBL1, retinoblastoma like 1 (p107), Retinoblastoma like protein 1
RBL1
IgG
Antigen Affinity Chromatography
Antibody
Videos
SDS
Documents

Documents

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