P2RX4 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 1A5A6, Proteintech

Catalog No.	Quantity
50-173-6843	150 μL

Catalog No. 50-173-6843 Supplier Proteintech Group Inc Supplier No. 664161IG150UL

Description

Mouse Monoclonal Antibody

The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP.

Specifications

• Antigen: P2RX4
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 1A5A6
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: P2RX4
• Gene Accession No.: P51577, Q99571, Q9JJX6
• Gene Alias: ATP receptor, P2RX4, P2X purinoceptor 4, P2X4, P2X4R, Purinergic receptor
• Gene Symbols: P2rx4
• Host Species: Mouse
• Immunogen: P2RX4 Fusion Protein Ag4445
• Purification Method: Protein A
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 100157723, 18438, 29659, 5025
• Target Species: Human, Mouse, Pig, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b