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Invitrogen™ P2Y12 Polyclonal Antibody
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Catalog No. PIPA595883
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PIPA595883 100 μL
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Catalog No. PIPA595883 Supplier Invitrogen™ Supplier No. PA595883
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Description

Rabbit Polyclonal Antibody

Positive Samples: U-251MG, HepG2, PC-12, DU145, Mouse brain, Rat testis; Cellular Location: Cell membrane, Multi-pass membrane protein Immunogen sequence: KSFRNSLISM L.

P2Y12 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene. Expression of P2Y12 has been reported in platelets, spinal cord, and many brain regions. ESTs for P2Y12 have been isolated from B-cell/lung/testis, brain, embryo, prostate, eye, kidney carcinoma, and colon carcinoma libraries.
TRUSTED_SUSTAINABILITY

Specifications

Antigen P2Y12
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 2.41 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene P2ry12
Gene Accession No. Q9CPV9, Q9EPX4, Q9H244
Gene Alias 2900079B22Rik; 4921504D23Rik; ADP-glucose receptor; ADPG-R; BDPLT8; Gi-coupled ADP receptor HORK3; G-protein coupled receptor SP1999; HORK3; P2RY12; P2T(AC); P2Y purinoceptor 12; P2Y(12)R; P2Y(AC); P2Y(ADP); P2Y(cyc); P2y12; P2Y12 platelet ADP receptor; P2YR12; purinergic receptor P2RY12; purinergic receptor P2Y, G-protein coupled 12; purinergic receptor P2Y, G-protein coupled, 12; purinergic receptor P2Y12; putative G-protein coupled receptor; SP1999
Gene Symbols P2ry12
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 243-342 of human P2RY12 (NP_7953451).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64803, 64805, 70839
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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