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Invitrogen™ P2Y12 Recombinant Rabbit Monoclonal Antibody (PSH04-48)
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Catalog No. MA562919
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MA562919 100 μL
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Catalog No. MA562919 Supplier Invitrogen™ Supplier No. MA562919
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: Human brain tissue, mouse brain tissue, rat brain tissue, mouse cerebrum tissue, mouse hippocampus tissue, rat cerebrum tissue. Tissue Specificity: Tissue enriched (brain). Subcellular Location: Cell membrane. Predicted band size: 39 kDa.

P2Y12 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene. Expression of P2Y12 has been reported in platelets, spinal cord, and many brain regions. ESTs for P2Y12 have been isolated from B-cell/lung/testis, brain, embryo, prostate, eye, kidney carcinoma, and colon carcinoma libraries.
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Specifications

Antigen P2Y12
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Multiplex Immunohistochemistry
Classification Recombinant Monoclonal
Clone PSH04-48
Concentration 1.09 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol, 0.1% BSA and 0.05% sodium azide; pH 7.4
Gene P2ry12
Gene Accession No. Q9CPV9, Q9EPX4, Q9H244
Gene Alias 2900079B22Rik; 4921504D23Rik; ADP-glucose receptor; ADPG-R; BDPLT8; Gi-coupled ADP receptor HORK3; G-protein coupled receptor SP1999; HORK3; P2RY12; P2T(AC); P2Y purinoceptor 12; P2Y(12)R; P2Y(AC); P2Y(ADP); P2Y(cyc); P2y12; P2Y12 platelet ADP receptor; P2YR12; purinergic receptor P2RY12; purinergic receptor P2Y, G-protein coupled 12; purinergic receptor P2Y, G-protein coupled, 12; purinergic receptor P2Y12; putative G-protein coupled receptor; SP1999
Gene Symbols P2ry12
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64803, 64805, 70839
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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