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Invitrogen™ p38 MAPK beta Monoclonal Antibody (P38-11A5)
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Catalog No. 338700
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Catalog No. Quantity
33-870-0 100 μg
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Catalog No. 33-870-0 Supplier Invitrogen™ Supplier No. 338700
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Description

Mouse Monoclonal Antibody

33-8700 has been successfully used in immunofluorescence and western blot. 33-8700 specifically recognizes the beta isoform of p38, with slight reactivity to p38-gamma.

MAPK11 (p38 beta) is a serine/threonine kinase which is involved in a variety of cellular processes, and is activated by proinflammatory cytokines and environmental stress. Mitogen-activated protein kinase 11. The protein encoded by p38 MAPK beta is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.
TRUSTED_SUSTAINABILITY

Specifications

Antigen p38 MAPK beta
Applications ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone P38-11A5
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.4
Gene MAPK11
Gene Accession No. Q15759, Q9WUI1
Gene Alias MAP kinase 11; MAP kinase p38 beta; MAPK 11; Mapk11; mitogen activated protein kinase 11; mitogen-activated protein kinase 11; Mitogen-activated protein kinase p38 beta; mitogen-activated protein kinase p38-2; OTTHUMP00000196655; p38-2; P38b; p38beta; P38BETA2; Prkm11; protein kinase, mitogen activated kinase, 11, p38beta; SAPK2; SAPK2b; Stress-activated protein kinase 2b; stress-activated protein kinase-2; stress-activated protein kinase-2b
Gene Symbols MAPK11
Host Species Mouse
Immunogen Recombinant, full-length human p38 beta-2; the product of the p38-beta gene.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19094, 5600
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1, IgG2a
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