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p600 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501562204
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50-156-2204 100 μL
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Catalog No. 50-156-2204 Supplier Bethyl Laboratories, Inc Supplier No. A302279A
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat

E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Regulates integrin-mediated signaling. May play a role in activation of FAK in response to cell-matrix interactions. Mediates ubiquitination of ACLY, leading to its subsequent degradation.

Specifications

Antigen p600
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 0.2 mg/ml
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene UBR4
Gene Accession No. Q5T4S7
Gene Alias 600 kDa retinoblastoma protein-associated factor, KIAA0462, KIAA1307, N-recognin-4, p600, RBAF600, retinoblastoma-associated factor 600-like protein, retinoblastoma-associated factor of 600 kDa, zinc finger UBR1-type protein 1, zinc finger, UBR1 type 1, ZUBR1
Gene Symbols UBR4
Host Species Rabbit
Immunogen Between 5133 and 5183
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23352
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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