P62/SQSTM1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Catalog No.	Quantity
50-553-750	150 μL

Catalog No. 50-553-750 Supplier Proteintech Group Inc Supplier No. 184201AP150UL

Description

Rabbit Polyclonal Antibody

The molecular weight of p62 is predicted to be 48/ 38 kDa (depending on the isoform), while western blot analyses using this antibody detects the bands around 45-48 kDa and 60-62 kDa, respectively.

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Specifications

• Antigen: P62/SQSTM1
• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
• Classification: Polyclonal
• Concentration: 0.29 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: SQSTM1
• Gene Accession No.: O08623, Q13501, Q64337
• Gene Alias: P62, sequestosome 1, SQSTM1, Ubiquitin binding protein p62
• Gene Symbols: Sqstm1
• Host Species: Rabbit
• Immunogen: P62/SQSTM1 Fusion Protein Ag13131
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 113894, 18412, 8878
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG