Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIMA528564

Invitrogen™ DUSP2 Monoclonal Antibody (PAC-1), FITC
GREENER_CHOICE

Catalog No. PIMA528564
Change view
Click to view available options
Quantity:
100 Tests
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIMA528564 100 Tests
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIMA528564 Supplier Invitrogen™ Supplier No. MA528564
Only null left
Add to Cart
Edge
Add to Cart

Description

Mouse Monoclonal Antibody

This antibody recognizes an extracellular activation-induced conformational epitope PAC-1 on CD41/CD61 complex (gpIIb/IIIa), also known as integrin alpha IIb beta 3, a receptor which mediates platelet aggregation. Recommended dilution is for 100 μL of whole blood or 1x10^6 cells in suspension.

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DUSP2
Applications Flow Cytometry
Classification Monoclonal
Clone PAC-1
Concentration 0.39 mg/mL
Conjugate FITC
Formulation TBS with 0.2% BSA and 15mM sodium azide; pH 8
Gene DUSP2
Gene Accession No. Q05923
Gene Alias dual specificity phosphatase 2; dual specificity protein phosphatase 2; Dual specificity protein phosphatase PAC-1; dual-specificity phosphatase 2; Dusp2; PAC1; Pac-1; serine/threonine specific protein phosphatase
Gene Symbols DUSP2
Host Species Mouse
Immunogen Human platelets.
Purification Method Size-exclusion chromatography
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1844
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgM κ
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.