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Invitrogen™ DUSP2 Monoclonal Antibody (PAC-1)
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Catalog No. PIMA528523
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100 μg
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Catalog No. Quantity
PIMA528523 100 μg
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Catalog No. PIMA528523 Supplier Invitrogen™ Supplier No. MA528523
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Description

Mouse Monoclonal Antibody

This antibody recognizes an extracellular activation-induced conformational epitope PAC-1 on CD41/CD61 complex (gpIIb/IIIa), also known as integrin alpha IIb beta 3, a receptor which mediates platelet aggregation.

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DUSP2
Applications Flow Cytometry, Immunoprecipitation, Immunocytochemistry
Classification Monoclonal
Clone PAC-1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 15mM sodium azide; pH 8
Gene DUSP2
Gene Accession No. Q05923
Gene Alias dual specificity phosphatase 2; dual specificity protein phosphatase 2; Dual specificity protein phosphatase PAC-1; dual-specificity phosphatase 2; Dusp2; PAC1; Pac-1; serine/threonine specific protein phosphatase
Gene Symbols DUSP2
Host Species Mouse
Immunogen Human platelets.
Purification Method Sequential chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1844
Target Species Human
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgM κ
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