Invitrogen™ PADI4 Monoclonal Antibody (OTI6A2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA526006

Catalog No. PIMA526006

Description

PADI4 Monoclonal Antibody for Western Blot, ICC/IF, IHC (P), Flow

Catalyzes the citrullination/deimination of arginine residues of proteins. Citrullinates histone H3 at 'Arg-8' and/or 'Arg-17' and histone H4 at 'Arg-3', which prevents their methylation by CARM1 and HRMT1L2/PRMT1 and represses transcription. Citrullinates EP300/P300 at 'Arg-2142', which favors its interaction with NCOA2/GRIP1.

Specifications

• Antigen: PADI4
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9UM07
• Gene Symbols: Padi4
• Immunogen: Human recombinant protein fragment corresponding to amnio acids 299-588 of PADI4 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: OTI6A2
• Conjugate: Unconjugated
• Gene: Padi4
• Gene Alias: HL-60 PAD; PAD; PAD type IV; PAD4; Padi4; PADI5; PADI-H protein; PAD-R4; Pdi4; PDI5; peptidyl arginine deiminase 4; peptidyl arginine deiminase, type 4; peptidyl arginine deiminase, type IV; peptidyl arginine deiminase, type V; peptidylarginine deiminase IV; Peptidylarginine deiminase type alpha; protein-arginine deiminase type IV; Protein-arginine deiminase type-4
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23569
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid