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Invitrogen™ PAK2 Polyclonal Antibody
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Catalog No. PIPA520274
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100 μg
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Catalog No. Quantity
PIPA520274 100 μg
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Catalog No. PIPA520274 Supplier Invitrogen™ Supplier No. PA520274
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Description

Rabbit Polyclonal Antibody

A suggested positive control is Jurkat cell lysate. PA5-20274 can be used with blocking peptide PEP-0389.

PAK2 (serine/threonine-protein kinase PAK2) is a serine/threonine kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis, or proliferation. It acts as a downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformation change and a subsequent autophosphorylation on several serine and/or threonine residues. Full-length PAK2 stimulates cell survival and cell growth. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PAK2
Applications Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Pak2
Gene Accession No. Q13177, Q64303, Q8CIN4
Gene Alias 5330420P17Rik; A130002K10Rik; AI836325; Alpha-PAK; Beta-PAK; C-t-PAK2; D16Ertd269e; gamma pak; gamma-PAK; mKIAA4182; Oligophrenin-3; OPHN3; p21 (CDKN1A)-activated kinase 2; p21 (RAC1) activated kinase 2; p21 protein (Cdc42/Rac)-activated kinase 2; p21-activated kinase 2; p27; p34; p58; p65-PAK; PAK alpha; PAK beta; PAK gamma; PAK1; PAK-1; Pak2; PAK-2; PAK-2p27; PAK-2p34; PAK3; PAK-3; PAK65; PAKgamma; S6/H4 kinase; serine/threonine-protein kinase PAK 2
Gene Symbols Pak2
Host Species Rabbit
Immunogen A 14 amino acid peptide from near the carboxy terminus of human PAK2.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 224105, 29432, 5062
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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