Invitrogen™ PAK7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA532965

Catalog No. PIPA532965

Description

Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Monkey (100%); Gibbon, Marmoset, Pig (94%); Dog, Panda, Horse, Rabbit (89%); Bovine, Bat, Elephant (83%). Immunohistochemistry with formalin-fixed paraffin-embedded tissues requires pretreatment with Proteinase K.

PAK7 (KIAA1264) is implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.

Specifications

• Antigen: PAK7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PAK5
• Gene Alias: 2900083L08Rik; 6430627N20; KIAA1264; p21 (CDKN1A)-activated kinase 7; p21 (RAC1) activated kinase 5; p21 (RAC1) activated kinase 7; p21 protein (Cdc42/Rac)-activated kinase 7; p21(CDKN1A)-activated kinase 7; p21-activated kinase 5; p21-activated kinase 7; p21CDKN1A-activated kinase 7; PAK 5; PAK 7; PAK5; PAK-5; Pak7; PAK-7; protein kinase PAK5; RP5-1119D9.3; Serine/threonine-protein kinase PAK 5; serine/threonine-protein kinase PAK 7; serine/threonine-protein kinase PAK7
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57144
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q9P286
• Gene Symbols: PAK5
• Immunogen: Synthetic 18 amino acid peptide from internal region of human PAK7.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG