Invitrogen™ Palladin Monoclonal Antibody (1E6)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA516141

Catalog No. PIMA516141

Description

Suggested positive control: MDA-MB231 (human breast cancer) lysates.

Palladin is a cytoskeletal protein required for organization of normal actin cytoskeleton. Palladin plays roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types. Palladin may function as a scaffolding molecule with the potential to impact both actin polymerization as well as the assembly of existing actin filaments into higher-order arrays. It binds to proteins that bind to either monomeric or filamentous actin. It localizes at sites where active actin remodeling takes place, such as lamellipodia and membrane ruffles. Palladin's different isoforms may have functional differences. It is also involved in the control of morphological and cytoskeletal changes associated with dendritic cell maturation.

Specifications

• Antigen: Palladin
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 0.05% sodium azide
• Gene Accession No.: P0C5E3, Q8WX93, Q9ET54
• Gene Symbols: PALLD
• Immunogen: Endogenous Palladin immunoprecipitated from chicken embryo fibroblasts.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Canine, Chicken
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: 1E6
• Conjugate: Unconjugated
• Gene: PALLD
• Gene Alias: 2410003B16Rik; 6030492A02; 90kDa actin-associated protein palladin; actin-associated protein palladin; CGI151; CGI-151; FLJ22190; FLJ38193; FLJ39139; involved in cytoskeletal assembly; KIAA0992; MYN; myoneurin; palladin; palladin isoform; palladin pseudogene; palladin, cytoskeletal associated protein; PALLD; PNCA1; Sarcoma antigen NY-SAR-77; SIH002
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 23022, 364558, 422428, 477351, 72333
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid