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  6. Invitrogen™ Pan Ras Monoclonal Antibody (Ras10)

Invitrogen™ Pan Ras Monoclonal Antibody (Ras10)

Catalog No. PIMA1012X
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20 μg
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PIMA1012X 20 μg
PIMA1012 100 μg
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Catalog No. PIMA1012X Supplier Invitrogen™ Supplier No. MA1012X
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Description

Mouse Monoclonal Antibody

This antibody recognizes normal p21, activated p21, and p21 from each of the Harvey, Kirsten and N-ras families.

This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Pan Ras
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone Ras10
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide
Gene HRAS
Gene Accession No. P01111, P01112, P01116, P08556, P32883, Q61411
Gene Alias AI929937; ALPS4; AV095280; C-BAS/HAS; cellular c-Ki-ras2; cellular c-Ki-ras2 proto-oncogene; CFC2; c-Ha-ras; c-Ha-ras p21 protein; c-Ha-ras transgene; C-HA-RAS1; c-has/bas p21 protein; C-H-RAS; c-Ki-ras; c-Kirsten-ras protein; c-Kirsten-ras proto-oncogene; c-K-ras; c-K-ras2 protein; CMNS; c-rasHa; c-ras-Ki-2 activated oncogene; CTLO; etID18709.8; fa04e08; fc14b12; fc23g10; fj89d12; fj99a10; GTP- and GDP-binding peptide B; GTPase HRas; GTPase HRas, N-terminally processed; GTPase Hras1; GTPase KRas; GTPase KRas, N-terminally processed; GTPase NRas; HAMSV; Ha-ras; Ha-Ras1 proto-oncoprotein; Harvey ras1 protein; Harvey rat sarcoma viral (v-Ha-ras) oncogene homolog; Harvey rat sarcoma viral oncogene homolog; Harvey rat sarcoma viral oncoprotein; Harvey rat sarcoma virus oncogene; Harvey rat sarcoma virus oncogene 1; Harvey-ras; hras; H-ras; H-ras 1 protein; HRas proto-oncogene, GTPase; HRas proto-oncogene, GTPase a; HRAS1; H-Ras-1; Hras-1; hrasa; H-RASIDX; hypothetical protein LOC445289; hypothetical protein LOC550286; K RAS; Ki-ras; Kirsten rat sarcoma oncogene 2, expressed; Kirsten rat sarcoma viral oncogene; Kirsten rat sarcoma viral oncogene homolog; Kirsten rat sarcoma viral oncogene homologue 2 (active); Kras; K-ras; K-Ras 2; K-ras p21 protein; KRAS proto-oncogene, GTPase; KRAS1; KRAS2; Kras-2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; NCMS; Neuroblastoma RAS; neuroblastoma ras oncogene; neuroblastoma RAS viral (v-ras) oncogene homolog; neuroblastoma RAS viral oncogene homolog; NRAS; N-ras; N-ras oncogene p21; N-ras protein part 4; NRAS proto-oncogene, GTPase; NRAS1; NS; NS3; NS6; oncogene KRAS2; p19 H-RasIDX protein; p21; p21 N-ras oncogene; p21 protein; p21B; p21ras; PR310 c-K-ras oncogene; RALD; ras; Ras family small GTP binding protein H-Ras; RASH1; RASK; RASK2; ras-like protein; RASN; sb:eu826; transformation gene: oncogene HAMSV; transforming protein N-Ras; Transforming protein p21; v-Ha-ras Harvey rat sarcoma viral oncogene homolog; v-Ha-ras Harvey rat sarcoma viral oncogene homolog a; v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog; v-ras neuroblastoma RAS viral oncogene homolog; wu:fa04e08; wu:fc14b12; wu:fc23g10; wu:fj89d12; wu:fj99a10; xRAS1; xRAS2; zgc:100761; zgc:110250; zgc:85725; zras-b1
Gene Symbols HRAS, KRAS, Nras
Host Species Mouse
Immunogen Purified recombinant Ras protein.
Purification Method Protein G
Quantity 20 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15461, 16653, 18176, 3265, 3845, 4893
Target Species Human, Mouse, Monkey
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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