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Description
Pannexin 1 Polyclonal Antibody for Western Blot, IHC
The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.
Specifications
| Pannexin 1 | |
| Polyclonal | |
| Unconjugated | |
| PANX1 | |
| AI847747; innexin; MRS1; Pannexin 1; pannexin-1; Panx1; px1; UNQ2529; UNQ2529/PRO6028 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 55991 | |
| -20°C | |
| Liquid |
| Immunohistochemistry, Western Blot | |
| 0.25 mg/mL | |
| PBS with 0.1% sodium azide; pH 7.4 | |
| Q9JIP4 | |
| PANX1 | |
| Synthetic peptide derived from the N-terminal region of the mouse Pannexin 1 protein (Accession# NP_062355), which is identical to rat and human sequences. | |
| 100 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG |
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