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Invitrogen™ Pannexin 1 Polyclonal Antibody
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Catalog No. 487900
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100 μg
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Catalog No. Quantity
48-790-0 100 μg
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Catalog No. 48-790-0 Supplier Invitrogen™ Supplier No. 487900
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Description

Rabbit Polyclonal Antibody

Pannexin 1 Polyclonal Antibody for Western Blot, IHC

The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Pannexin 1
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.4
Gene PANX1
Gene Accession No. Q9JIP4
Gene Alias AI847747; innexin; MRS1; Pannexin 1; pannexin-1; Panx1; px1; UNQ2529; UNQ2529/PRO6028
Gene Symbols PANX1
Host Species Rabbit
Immunogen Synthetic peptide derived from the N-terminal region of the mouse Pannexin 1 protein (Accession# NP_062355), which is identical to rat and human sequences.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55991
Target Species Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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