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Invitrogen™ Pannexin 1 Polyclonal Antibody
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Catalog No. 488100
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100 μg
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Catalog No. Quantity
48-810-0 100 μg
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Catalog No. 48-810-0 Supplier Invitrogen™ Supplier No. 488100
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Description

Rabbit Polyclonal Antibody

Pannexin 1 Polyclonal Antibody for Western Blot, IHC

The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Pannexin 1
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.4
Gene PANX1
Gene Accession No. Q9JIP4
Gene Alias AI847747; innexin; MRS1; Pannexin 1; pannexin-1; Panx1; px1; UNQ2529; UNQ2529/PRO6028
Gene Symbols PANX1
Host Species Rabbit
Immunogen Synthetic peptide derived from the C-terminal region of the mouse Pannexin 1 protein (Accession# NP_062355), which is identical to rat and 92% homologous to human sequence.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55991
Target Species Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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