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CPC Scientific H-Ala-Tyr-Pro-Gly-Lys-Phe-NH2
(trifluoroacetate salt) 5MG
Supplier: CPC Scientific PARP015B
This peptide based on the proteolytically-revealed tethered ligand sequence of the murine proteinase-activated receptor-4 (PAR-4) was shown to cause platelet aggregation with an EC50 value of about 15 M. PAR-4 agonist peptide stimulates thromboxane production by human platelets with the maximal response to this agonist being approximately half of that observed after maximal thrombin stimulation.SEQUENCE: H-Ala-Tyr-Pro-Gly-Lys-Phe-NH2 (trifluoroacetate salt)ONE-LETTER SEQUENCE: AYPGKF-NH2MOLECULAR FORMULA: C34H48N8O7MOLECULAR WEIGHT: 680.8STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [352017-71-1]SYNONYMS: RESEARCH AREA: HematologyREFERENCES:T.R.Faruqi et al., J. Biol. Chem., 275, 19728 (2000)M.D.Hollenberg and M.Saifeddine, Can. J. Physiol. Pharmacol., 79, 439 (2001)R.A.Henriksen and V.K.Hanks, Arterioscler. Thromb. Vasc. Biol., 22, 861 (2002)Sabri, A. et al. J. Biol. Chem. 278, 11714 (2003)Ma, L. et al. Proc. Natl. Acad. Sci. USA 102, 216 (2005)SKU(s):
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