PARK2/Parkin Mouse anti-Human, Mouse, Clone: 2H5A7, Proteintech

Catalog No.	Quantity
50-173-7091	150 μL

Catalog No. 50-173-7091 Supplier Proteintech Group Inc Supplier No. 666741IG150UL

Description

Mouse Monoclonal Antibody

The precise function of Parkin gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.

Specifications

• Antigen: PARK2/Parkin
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 2H5A7
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: PRKN
• Gene Accession No.: O60260
• Gene Alias: AR JP, LPRS2, PARK2, Parkinson disease protein 2, PDJ, PRKN
• Gene Symbols: Park2, PRKN
• Host Species: Mouse
• Immunogen: PARK2/Parkin Fusion Protein Ag5179
• Purification Method: Protein A
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5071, 50873
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b