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Invitrogen™ PARP6 Polyclonal Antibody
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Catalog No. PIPA5107209
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PIPA5107209 100 μL
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Catalog No. PIPA5107209 Supplier Invitrogen™ Supplier No. PA5107209
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Description

Rabbit Polyclonal Antibody

Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%.

Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. Poly(ADP-ribose) polymerases (PARPs) now constitute a large family of 18 proteins, encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs now extends considerably the field of poly(ADP-ribosyl)ation reactions to various aspects of the cell biology including cell proliferation and cell death. Some of these new members interact with each other, share common partners and common subcellular localizations suggesting possible fine tuning in the regulation of this post-translational modification of proteins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PARP6
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
Gene Parp6
Gene Accession No. Q2NL67
Gene Alias 1700119G14Rik; 2310028P13Rik; 3110038K10Rik; ADP-ribosyltransferase diphtheria toxin-like 17; ARTD17; C030013N01Rik; PARP6; PARP-6; PARP-6-B1; PARP-6-C; pART17; poly (ADP-ribose) polymerase family, member 6; poly [ADP-ribose] polymerase 6; poly(ADP-ribose) polymerase family member 6; Protein mono-ADP-ribosyltransferase PARP6; RGD1310937
Gene Symbols Parp6
Host Species Rabbit
Immunogen Synthetic peptide directed towards the C-terminal region of human PARP6.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56965
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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