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Tocris Bioscience™ PARPi-FL
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Catalog No. 64611
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64-611 1 mg
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Catalog No. 64-611 Supplier Tocris Bioscience™ Supplier No. 6461/1
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Description

Potent fluorescent PARP inhibitor

PARPi-FL is a fluorescent potent PARP inhibitor (IC50 = 12 nM). Composed of a PARP inhibitor conjugated to BDY FL, SE (Cat. No. 5465). Colocalizes with PARP immunostaining in multiple cancer cell lines in vivo and accumulates in tumor cells and tumor associated macrophages. Enables high temporal and subcellular spatial resolution of drug distribution. Emission max = 525 nm. Cell permeable.

Specifications

Chemical Name or Material (T-4)-[4-[[3-[[4-[3-[5-[(3,5-Dimethyl-2H-pyrrol-2-ylidene-κN)methyl]-1H-pyrrol-2-yl-κN-1-oxopropyl]-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinonato]difluoroboron
CAS 1380359-84-1
Quantity 1 mg
Molecular Formula C34H32BF3N6O3
Formula Weight 640.46
Purity 90%
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